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Alzheimer's Disease

Some researchers refer to Alzheimer's disease as "type 3 diabetes" because insulin resistance appears to play a role in its development. Brain cells become less responsive to insulin, leading to impaired energy metabolism and accumulation of beta-amyloid plaques. Emerging evidence suggests that ketogenic diets, which provide ketones as an alternative fuel, may improve cognitive function in individuals with mild cognitive impairment or Alzheimer's disease.1

  1. Kashiwaya, Y., et al. (2013). A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease. Neurobiology of Aging, 34(6), 1530-1539. ↩